The truth may be puzzling. It may take some work to grapple with. It may be counterintuitive. It may contradict deeply held prejudices. It may not be consonant with what we desperately want to be true. But our preferences do not determine what's true.

But the fact that some geniuses were laughed at does not imply that all who are laughed at are geniuses. They laughed at Columbus, they laughed at Fulton, they laughed at the Wright Brothers. But they also laughed at Bozo the Clown.

The nuclear arms race is like two sworn enemies standing waist deep in gasoline, one with three matches, the other with five.

The evidence, so far at least and laws of Nature aside, does not require a Designer. Maybe there is one hiding, maddeningly unwilling to be revealed.

We invest far off places with a certain romance... Long summers, mild winters, rich harvests, plentiful game; none of them lasts for ever. Your own life, or your bands, or even your species - might be owed to a restless few, drawn by a craving they can hardly articulate or understand, to undiscovered lands, and new worlds.

In college, in the early 1950s, I began to learn a little about how science works, the secrets of its great success, how rigorous the standards of evidence must be if we are really to know something is true, how many false starts and dead ends have plagued human thinking, how our biases can colour our interpretation of evidence, and how often belief systems widely held and supported by the political, religious and academic hierarchies turn out to be not just slightly in error, but grotesquely wrong.

While our behavior is still significantly controlled by our genetic inheritance, we have, through our brains, a much richer opportunity to blaze new behavioral and cultural pathways on short timescales.