In the way that scepticism is sometimes applied to issues of public concern, there is a tendency to belittle, to condescend, to ignore the fact that, deluded or not, supporters of superstition and pseudoscience are human beings with real feelings, who, like the sceptics, are trying to figure out how the world works and what our role in it might be. Their motives are in many cases consonant with science. If their culture has not given them all the tools they need to pursue this great quest, let us temper our criticism with kindness. None of us comes fully equipped.

The Cosmos is all that is or ever was or ever will be.

But amid much elegance and precision, the details of life and the Universe also exhibit haphazard, jury-rigged arrangements and much poor planning. What shall we make of this: an edifice abandoned early in construction by the architect?

My fundamental premise about the brain is that its workings - what we sometimes call "mind" - are a consequence of its anatomy and physiology, and nothing more.

How is it that hardly any major religion has looked at science and concluded, “This is better than we thought! The Universe is much bigger than our prophets said, grander, more subtle, more elegant?” Instead they say, “No, no, no! My god is a little god, and I want him to stay that way.” A religion, old or new, that stressed the magnificence of the Universe as revealed by modern science might be able to draw forth reserves of reverence and awe hardly tapped by the conventional faiths.

'In his celebrated book, 'On Liberty', the English philosopher John Stuart Mill argued that silencing an opinion is "a peculiar evil." If the opinion is right, we are robbed of the "opportunity of exchanging error for truth"; and if it's wrong, we are deprived of a deeper understanding of the truth in its "collision with error." If we know only our own side of the argument, we hardly know even that: it becomes stale, soon learned by rote, untested, a pallid and lifeless truth.'

In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion.