Even Johannes Kepler, Isaac Newton, Charles Darwin, Gregor Mendel, and Albert Einstein made serious mistakes. But the scientific enterprise arranges things so that teamwork prevails: What one of us, even the most brilliant among us, misses, another of us, even someone much less celebrated and capable, may detect and rectify.

The well-meaning contention that all ideas have equal merit seems to me little different from the disastrous contention that no ideas have any merit.

[Science] is not perfect. It can be misused. It is only a tool. But it is by far the best tool we have, self-correcting, ongoing, applicable to everything. It has two rules. First: there are no sacred truths; all assumptions must be critically examined; arguments from authority are worthless. Second: whatever is inconsistent with the facts must be discarded or revised. ... The obvious is sometimes false; the unexpected is sometimes true.

There is in this Universe much of what seems to be design.

For all its material advantages, the sedentary life has left us edgy, unfulfilled, even after 400 generations in villages and cities, we haven't forgotten: The open road still softly calls like a nearly forgotten song of childhood.

All of the rocky and metallic material we stand on, the iron in our blood, the calcium in our teeth, the carbon in our genes were produced billions of years ago in the interior of a red giant star. We are made of star stuff.

We've begun at last to wonder about our origins, star stuff contemplating the stars, organized collections of ten billion billion billion atoms contemplating the evolution of matter, tracing that long path by which it arrived at consciousness here on the planet Earth and perhaps throughout the cosmos. Our obligation to survive and flourish is owed not just to ourselves but also to that cosmos, ancient and vast, from which we spring.