One of the saddest lessons of history is this: If we’ve been bamboozled long enough, we tend to reject any evidence of the bamboozle. We’re no longer interested in finding out the truth. The bamboozle has captured us. It’s simply too painful to acknowledge, even to ourselves, that we’ve been taken. Once you give a charlatan power over you, you almost never get it back.

She had studied the universe all her life, but had overlooked its clearest message: For small creatures such as we the vastness is bearable only through love.

I worry that, especially as the Millennium edges nearer, pseudo-science and superstition will seem year by year more tempting, the siren song of unreason more sonorous and attractive.

There is a reward structure in science that is very interesting: Our highest honors go to those who disprove the findings of the most revered among us. So Einstein is revered not just because he made so many fundamental contributions to science, but because he found an imperfection in the fundamental contribution of Isaac Newton.

There are naive questions, tedious questions, ill-phrased questions, questions put after inadequate self-criticism. But every question is a cry to understand the world. There is no such thing as a dumb question.

If intelligence is our only edge, we must learn to use it better, to shape it, to understand its limitations and deficiencies -- to use it as cats use stealth, as katydids use camouflage -- to make it the tool of our survival.

There is a lurking fear that some things are not “meant" to be known, that some inquiries are too dangerous for human beings to make.