The wind whips through the canyons of the American Southwest, and there is no one to hear it but us - a reminder of the 40,000 generations of thinking men and women who preceded us, about whom we know almost nothing, upon whom our civilization is based.

Science is far from a perfect instrument of knowledge. It's just the best we have.

The Apollo pictures of the whole Earth conveyed to multitudes something well known to astronomers: On the scale of the worlds - to say nothing of stars or galaxies - humans are inconsequential, a thin film of life on an obscure and solitary lump of rock and metal

For me, the most ironic token of [the first human moon landing] is the plaque signed by President Richard M. Nixon that Apollo 11 took to the moon. It reads, ‘We came in peace for all Mankind.’ As the United States was dropping seven and a half megatons of conventional explosives on small nations in Southeast Asia, we congratulated ourselves on our humanity. We would harm no one on a lifeless rock.

Once we overcome our fear of being tiny, we find ourselves on the threshold of a vast and awesome Universe that utterly dwarfs — in time, in space, and in potential — the tidy anthropocentric proscenium of our ancestors.

Books tap the wisdom of our species -- the greatest minds, the best teachers -- from all over the world and from all our history. And they're patient.

We can judge our progress by the courage of our questions and the depth of our answers, our willingness to embrace what is true rather than what feels good.