[N]o scientist likes to be criticized. ... But you don't reply to critics: "Wait a minute, wait a minute; this is a really good idea. I'm very fond of it. It's done you no harm. Please don't attack it." That's not the way it goes. The hard but just rule is that if the ideas don't work, you must throw them away. Don't waste any neurons on what doesn't work. Devote those neurons to new ideas that better explain the data. Valid criticism is doing you a favor.

There are as many atoms in one molecule of DNA as there are stars in a typical galaxy.

The near side of a galaxy is tens of thousands of light-years closer to us than the far side; thus we see the front as it was tens of thousands of years before the back. But typical events in galactic dynamics occupy tens of millions of years, so the error in thinking of an image of a galaxy as frozen in one moment of time is small.

Centuries hence, when current social and political problems may seem as remote as the problems of the Thirty Years' War are to us, our age may be remembered chiefly for one fact: It was the time when the inhabitants of the earth first made contact with the vast cosmos in which their small planet is embedded.

Humans — who enslave, castrate, experiment on, and fillet other animals — have had an understandable penchant for pretending animals do not feel pain. A sharp distinction between humans and 'animals' is essential if we are to bend them to our will, make them work for us, wear them, eat them — without any disquieting tinges of guilt or regret. It is unseemly of us, who often behave so unfeelingly toward other animals, to contend that only humans can suffer. The behavior of other animals renders such pretensions specious. They are just too much like us.

The Bill of Rights decoupled religion from the state, in part because so many religions were steeped in an absolutist frame of mind - each convinced that it alone had a monopoly on the truth and therefore eager for the state to impose this truth on others.

We invest far off places with a certain romance... Long summers, mild winters, rich harvests, plentiful game; none of them lasts for ever. Your own life, or your bands, or even your species - might be owed to a restless few, drawn by a craving they can hardly articulate or understand, to undiscovered lands, and new worlds.