In 1494, King Charles VIII of France invaded Italy. Within months, his army collapsed and fled. It was routed not by the Italian army but by a microbe. A mysterious new disease spread through sex killed many of Charlesโs soldiers and left survivors weak and disfigured. French soldiers spread the disease across much of Europe, and then it moved into Africa and Asia. Many called it the French disease. The French called it the Italian disease. Arabs called it the Christian disease. Today, it is called syphilis.
Carl ZimmerAt long last, we may be returning to the original two-sided sense of the word virus, which originally signified either a life-giving substance or a deadly venom. Viruses are indeed exquisitely deadly, but they have provided the world with some of its most important innovations. Creation and destruction join together once more.
Carl ZimmerI wouldn't be a very good hunter without these glasses. I'm not a very good hunter with these glasses, but I'd be even worse without them, so that would put a crimp in how many kids I could have, so all of these medical advances have at least in some parts of the world blunted natural selection.
Carl ZimmerOne of the big challenges now is to figure out just how many viruses there really are in the human genome. So far the estimate is 8.3% of our genome is virus, but it actually could be a lot higher.
Carl ZimmerThere is some research that suggests that viruses like the flu are really actually kind of at the razor's edge when it comes to mutation. They're mutating so fast that if they mutated much faster they would actually develop a lot of harmful mutations that could slow them down and cripple them and eventually literally drive them extinct.
Carl Zimmer