One of the big challenges now is to figure out just how many viruses there really are in the human genome. So far the estimate is 8.3% of our genome is virus, but it actually could be a lot higher.
Carl ZimmerIn 1494, King Charles VIII of France invaded Italy. Within months, his army collapsed and fled. It was routed not by the Italian army but by a microbe. A mysterious new disease spread through sex killed many of Charlesโs soldiers and left survivors weak and disfigured. French soldiers spread the disease across much of Europe, and then it moved into Africa and Asia. Many called it the French disease. The French called it the Italian disease. Arabs called it the Christian disease. Today, it is called syphilis.
Carl ZimmerBorna virus is not a retrovirus. It doesn't actually insert its own genes into our cells. What it does is just hangs out near our DNA and uses some of the molecular machinery to copy itself.
Carl ZimmerIf you're looking for your own idea of your own identity you know the human genome may not be the best place to look for it. You're just looking at a bunch of viruses.
Carl ZimmerAbout 1.2% of the human genome is made up of genes, things that encode for proteins, the stuff that we consider us. There is about 8.3% that's a virus. In other words we're probably about seven times more virus than we are human genes, which is kind of a weird way to thinking about yourself.
Carl Zimmer