But I do believe architecture, and all art, should be content-driven. It should have something to say beyond the sensational.

I'd been to Stourhead and was inspired by the perfect parity between architecture and art; in fact, the architecture is the art. I wrote a piece called 'Not Sculpture Park,' because most of these things become car parks for bought-in sculpture. The artists should be working with the site, not just plonking pieces down.

I've been a lucky man. I've only faced one real tragedy: the death of my wife, Maggie, from cancer in 1995.

Science is a victim of its own reductive metaphors: 'Big Bang,' 'selfish gene' and so on. Richard Dawkins' selfish gene fitted with the Thatcherite politics of the time. It should actually be the 'altruistic gene,' but he'd never have sold as many books with a title like that.

The cell is a city of production centres, each part working away like mad, and it's co-ordinated. Six trillion cells in a body - you can't help but be moved.

The rule seems to be that there are no absolutes, that what is rare is prized. Thus, in times of relative affluence, thin models become dominant.

You have to believe in a placebo or it wont work, but if it works, its obviously working in some indirect way, through feedback in the immune system, let us say, or in the willpower of the patient to take a more strenuous exercise in their own therapy.