Almost everything worthwhile carries with it some sort of risk, whether it's starting a new business, whether it's leaving home, whether it's getting married, or whether it's flying in space.

I'm not a wealthy person and I don't think that I would be able to prioritize that much money to go for a ride to a place that I have already lived. But if the price comes down or I win a lottery or something, why not?

I've had a chance to fly a lot of different airplanes, but it was nothing like the shuttle ride.

No one ever accomplished anything great sitting down.

Other anatomical changes associated with long-duration space flight are definitely negative: the immune system weakens, the heart shrinks because it doesn't have to strain against gravity, eyesight tends to degrade, sometimes markedly (no one's exactly sure why yet). The spine lengthens as the little sacs of fluid between the vertebrae expand, and bone mass decreases as the body sheds calcium. Without gravity, we don't need muscle and bone mass to support our own weight, which is what makes life in space so much fun but also so inherently bad for the human body, long-term.

Fatherhood is the unending imperfect task of turning yourself into your dad while secretly maintaining the unbridled elation of your boyhood

There's really just one thing I can control: my attitude during the journey, which is what keeps me feeling steady and stable, and what keeps me headed in the right direction. So I consciously monitor and correct, if necessary, because losing attitude would be far worse than not achieving my goal.