The cool things about space is when you put your pants on here, you can put them on two legs at a time.

One Chief Astronaut used to make a point of phoning the front desk at the clinic where applicants are sent for medical testing, to find out which ones treated the staff well-and which ones stood out in a bad way. The nurses and clinic staff have seen a whole lot of astronauts over the years, and they know what the wrong stuff looks like. A person with a superiority complex might unwittingly, right there in the waiting room, quash his or her chances of ever going to space.

Competence means keeping your head in a crisis, sticking with a task even when it seems hopeless, and improvising good solutions to tough problems when every second counts. It encompasses ingenuity, determination and being prepared for anything.

Sweat the small stuff. Without letting anyone see you sweat.

Almost everything worthwhile carries with it some sort of risk.

I'm not a wealthy person and I don't think that I would be able to prioritize that much money to go for a ride to a place that I have already lived. But if the price comes down or I win a lottery or something, why not?

Other anatomical changes associated with long-duration space flight are definitely negative: the immune system weakens, the heart shrinks because it doesn't have to strain against gravity, eyesight tends to degrade, sometimes markedly (no one's exactly sure why yet). The spine lengthens as the little sacs of fluid between the vertebrae expand, and bone mass decreases as the body sheds calcium. Without gravity, we don't need muscle and bone mass to support our own weight, which is what makes life in space so much fun but also so inherently bad for the human body, long-term.