In systemic searches for embryonic lethal mutants of Drosophila melanogaster we have identified 15 loci which when mutated alter the segmental patterns of the larva. These loci probably represent the majority of such genes in Drosophila. The phenotypes of the mutant embryos indicate that the process of segmentation involves at least three levels of spatial organization: the entire egg as developmental unit, a repeat unit with the length of two segments, and the individual segment.

I think there is too much attention on mentoring. If people want to be scientists, they will figure out how to do it. They need to figure it out by themselves.

I was raised with this idea of hard work and keeping doors open. To be able to choose what you want to do in the future. That was what we tried to tell our children, too.

The three of us have worked on the development of the small and totally harmless fruit fly, Drosophila. This animal has been extremely cooperative in our hands - and has revealed to us some of its innermost secrets and tricks for developing from a single celled egg to a complex living being of great beauty and harmony. ... None of us expected that our work would be so successful or that our findings would ever have relevance to medicine.

I immediately loved working with flies. They fascinated me, and followed me around in my dreams.

I know labs where women refuse to make a coffee for others because they don't want to be seen doing seemingly female things. I think this is stupid. Why not make a coffee, bring a cake? I do it.

The drive to want to know is innate in people. You cannot influence this. I think in contrast it is harmful if you push kids too far in a particular direction.