In the brute physical world, and the one encompassed by medicine, there are all too many things that could kill you, don't kill you, and then leave you considerably weaker.

In the early days of the December that my father was to die, my younger brother brought me the news that I was a Jew. I was then a transplanted Englishman in America, married, with one son and, though unconsoled by any religion, a nonbelieving member of two Christian churches. On hearing the tidings, I was pleased to find that I was pleased.

The pre-history of our species is hag-ridden with episodes of nightmarish ignorance and calamity, for which religion used to identify, not just the wrong explanation, but the wrong culprit. Human sacrifices were made preeminently in times of epidemics, useless prayers were uttered, bogus miracles attested to, and scapegoats - such as Jews or heretics or witches - hunted down and burned.

There either is a god or there is not; there is a 'design' or not.

Distrust compassion; prefer dignity for yourself and others. Don't be afraid to be thought arrogant or selfish.

Avoid stock expressions (like the plague, as William Safire used to say) and repetitions. Don't say that as a boy your grandmother used to read to you, unless at that stage of her life she really was a boy, in which case you have probably thrown away a better intro. If something is worth hearing or listening to, it's very probably worth reading. So, this above all: Find your own voice.

Thanks to the telescope and the microscope, religion no longer offers an explanation for anything important.