Ardent desire for knowledge, in fact, is the one motive attracting and supporting investigators in their efforts; and just this knowledge, really grasped and yet always flying before them, becomes at once their sole torment and their sole happiness. Those who do not know the torment of the unknown cannot have the joy of discovery which is certainly the liveliest that the mind of man can ever feel.

The true worth of an experimenter consists in his pursuing not only what he seeks in his experiment, but also what he did not seek.

In these researches I followed the principles of the experimental method that we have established, i.e., that, in presence of a well-noted, new fact which contradicts a theory, instead of keeping the theory and abandoning the fact, I should keep and study the fact, and I hastened to give up the theory.

The experimenter who does not know what he is looking for will not understand what he finds.

Science increases our power in proportion as it lowers our pride.

When we meet a fact which contradicts a prevailing theory, we must accept the fact and abandon the theory, even when the theory is supported by great names and generally accepted.

The physiologist is not a man of the world, he is a scientist, a man caught and absorbed by a scientific idea that he pursues; he no longer hears the cries of the animals, no longer sees the flowing blood, he sees only his idea: organisms that hide from him problems that he wants to discover. He doesn't feel that he is in a horrible carnage; under the influence of a scientific idea, he pursues with delight a nervous filament inside stinking and livid flesh that for any other person would be an object of disgust and horror.