It is impossible to devise an experiment without a preconceived idea; devising an experiment, we said, is putting a question; we never conceive a question without an idea which invites an answer. I consider it, therefore, an absolute principle that experiments must always be devised in view of a preconceived idea, no matter if the idea be not very clear nor very well defined.
Claude BernardEven mistaken hypotheses and theories are of use in leading to discoveries. This remark is true in all the sciences. The alchemists founded chemistry by pursuing chimerical problems and theories which are false. In physical science, which is more advanced than biology, we might still cite men of science who make great discoveries by relying on false theories.
Claude BernardThe first requirement in using statistics is that the facts treated shall be reduced to comparable units.
Claude BernardWhen a physician is called to a patient, he should decide on the diagnosis, then the prognosis, and then the treatment. ... Physicians must know the evolution of the disease, its duration and gravity in order to predict its course and outcome. Here statistics intervene to guide physicians, by teaching them the proportion of mortal cases, and if observation has also shown that the successful and unsuccessful cases can be recognized by certain signs, then the prognosis is more certain.
Claude BernardThe science of life is a superb and dazzlingly lighted hall which may be reached only by passing through a long and ghastly kitchen.
Claude BernardThe physiologist is not a man of the world, he is a scientist, a man caught and absorbed by a scientific idea that he pursues; he no longer hears the cries of the animals, no longer sees the flowing blood, he sees only his idea: organisms that hide from him problems that he wants to discover. He doesn't feel that he is in a horrible carnage; under the influence of a scientific idea, he pursues with delight a nervous filament inside stinking and livid flesh that for any other person would be an object of disgust and horror.
Claude Bernard