I'm very proud that President [George W.] Bush took on AIDS relief. It was the largest single response by any country to a major international health crisis, and there are millions of people who are alive today in Africa and other developing countries because of that program.

I'm very glad my mother didn't let me quit piano lessons at age 10. She said I wasn't old enough or good enough to make that decision, and she was right. I remember at the time I was shocked. I did not like that my mother said those things to me. But when I got a chance to play with Yo-Yo Ma or more recently with Aretha Franklin, I thought, I'm really glad she said what she did.

I really wish that we had passed a comprehensive immigration bill because that would've really helped our country.

The PDB (Bin Laden Determined to Strike in U.S.) does not say the United States is going to be attacked. It says Bin Laden would like to attack the United States. I don't think you, frankly, had to have that report to know that Bin Laden would like to attack the United States.

I believed Afghanistan was always going to be hard. It's the fifth poorest country in the world. And when you fly over it, you realize that there's not much there. And, of course, it has the problem, too, of being on that border with Pakistan in basically an ungoverned region that has given the terrorists a staging ground. So it's a very difficult place. But I do believe that the mission there can succeed if success is defined as helping the Afghans to prevent the Taliban from being an existential threat to the Afghan government.

Differences can be strength rather than a handicap.

I don't think anybody could have predicted that they would try to use an airplane as a missile, a hijacked airplane as a missile.