Most days are not overwhelmingly successful in your life. And what really marks whether you're going to be successful is how well you deal with the bad days, not how well you deal with the good ones.

We have to recognize that the reason that the global order that we've enjoyed and almost take for granted over the last several years exists is that after World War II, the United States and its allies tried to build an antidote to what they had seen between World War I and World War II. There, they'd seen protectionism, beggar-thy-neighbor trading policies, so they said, we'll build an open international economy. And they did that.

I'm very proud that President [George W.] Bush took on AIDS relief. It was the largest single response by any country to a major international health crisis, and there are millions of people who are alive today in Africa and other developing countries because of that program.

We're all products of our environment, and I suspect that strength of will - the feeling, "I'm going to be able to do whatever you put in front of me" - is honed in an environment where not everything is easy. Ironically, growing up in that environment, you don't have a sense of aggrievement or entitlement. You just have a sense of overcoming.

When you have big historic changes, there are going to be ups and downs... There are going to be peaks and valleys. Some things are going to go right. Some things are going to go wrong. But as long as the strategic direction is going in the right way, that's really what you have to judge.

I feel that we're dividing along class lines for the first time in our history. Now one thing that has happened in this reaction to globalization is that the elites are not respectful of the values of those who are ordinary citizens, so we seem to be dividing ourselves into ever-smaller identity groups, each with its own narrative, each with its own grievance, and that's a problem.

We can't afford to let the international community and the world lose faith in the diplomatic track.