True, you don't have to be religious to be crazy, but it helps.

We should get used to the idea that we'll probably never be able to find - and confirm - a good explanation of the ultimate origin of the universe, though I see no reason to believe that we can't press much further on this question than we have managed to date.

In order to make a perfect and beautiful machine, it is not requisite to know how to make it. All the works of human genius can be understood in the end to be products of a cascade of generate-and-test procedures that are, at bottom, algorithmic and mindless.

I should emphasize this, to keep well-meaning but misguided multiculturalists at bay: the theoretical entities in which these tribal people frankly believe — the gods and other spirits — don't exist. These people are mistaken, and you know it as well as I do. It is possible for highly intelligent people to have a very useful but mistaken theory, and we don't have to pretend otherwise in order to show respect for these people and their ways.

The evidence for evolution pours in, not only from geology, paleontology, biogeography, and anatomy, but of course from molecular biology and every other branch of the life sciences.

The traditional view of purpose says it comes from on high, from God, from the Creator. Darwin's idea of natural selection makes people uncomfortable because it reverses the direction of tradition. Whereas people used to think of meaning coming from on high and being ordained from the top down, now we have Darwin saying, "No, all of this design can happen, all of this purpose can emerge from the bottom up without any direction at all."

Whereas religions may serve a benign purpose by letting many people feel comfortable with the level of morality they themselves can attain, no religion holds its member to the high standards of moral responsibility that the secular world of science and medicine does!