I guess because I had such a horrible life growing up, going from place to place not knowing what I was gonna do and ending up being homeless, there was a lot of pain and a lot of anger that was coming out through my guitar playing.

It wasn't enough for Megadeth to do well; I wanted Metallica to fail.

People say that being kicked out of Metallica is what drove me to be better and faster in Megadeth, but i was faster and better than Metallica when i was in Metallica

God created whammy bars for people who don't know how to solo.

Playing acoustic guitar is like having sex with your clothes on. I mean you know how to do it, but it’s more difficult.

The guitar influence that affected my songwriting came from the New Wave of British Heavy Metal.

Buckethead [former GUNS N' ROSES guitarist] is probably twice as good a guitar player as me and Slash combined, and can stand having fried chicken rubbed up against his face all night for a couple of hours.