The measure of (mental) health is flexibility (not comparison to some 'norm'), the freedom to learn from experience ... to be influenced by reasonable arguments ... and the appeal to the emotions ... and especially the freedom to cease when sated. The essence of illness is the freezing of behavior into unalterable and insatiable patterns.

The fundamental premise of sci-fi is not spaceships and lasers - it's that children can learn from the mistakes of their parents.

Self-awareness is probably overrated. A complex, self-regulating system doesn't need it in order to be successful, or even smart.

...where were answers to the truly deep questions? Religion promised those, though always in vague terms, while retreating from one line in the sand to the next. Don't look past this boundary, they told Galileo, then Hutton, Darwin, Von Neumann, and Crick, always retreating with great dignity before the latest scientific advance, then drawing the next holy perimeter at the shadowy rim of knowledge.

The sane are usually attracted by other things than power.

When I begin a book, I inevitably discover many things along the way, about the characters, their past histories and the political intrigues that surround them. This discovery process is vital, and I would not prejudice it by deciding too much in advance

For all its beauty, honesty, and effectiveness at improving the human condition, science demands a terrible price - that we accept what experiments tell us about the universe, whether we like it or not. It's about consensus and teamwork and respectful critical argument, working with, and through, natural law. It requires that we utter, frequently, those hateful words - 'I might be wrong.'