But honestly, if you do a rigorous survey of my work, I'll bet you'll find that biology is a theme far more often than physical science.

For all its beauty, honesty, and effectiveness at improving the human condition, science demands a terrible price - that we accept what experiments tell us about the universe, whether we like it or not. It's about consensus and teamwork and respectful critical argument, working with, and through, natural law. It requires that we utter, frequently, those hateful words - 'I might be wrong.'

...where were answers to the truly deep questions? Religion promised those, though always in vague terms, while retreating from one line in the sand to the next. Don't look past this boundary, they told Galileo, then Hutton, Darwin, Von Neumann, and Crick, always retreating with great dignity before the latest scientific advance, then drawing the next holy perimeter at the shadowy rim of knowledge.

It's how creativity works. Especially in humans. For every good idea, ten thousand idiotic ones must first be posed, sifted, tried out, and discarded. A mind that's afraid to toy with the ridiculous will never come up with the brilliantly original.

The best time to act on this was decades ago. The second best time is now.

Every marvel of our age arose out of the critical give and take of an open society. No other civilization ever managed to incorporate this crucial innovation, weaving it into daily life. And if you disagree with this... say so!

Reciprocal accountability, or criticism [is] the only known antidote to error.