I've never had writer's block.

That's the one for my tombstone... Here lies David Byrne. Why the big suit?

My personal feeling is that human beings have this incredible capacity for denial.

It's a fundamental, social attitude that the 1% supports symphonies and operas and doesn't support Johnny learning to program hip-hop beats. When I put it like that, it sounds like, 'Well, yeah,' but you start to think, 'Why not, though?' What makes one more valuable than another?

The voting booth joint is a great leveler; the whole neighborhood - rich, poor, old, young, decrepit and spunky - they all turn out in one day.

When you fall in love, you feel like a missing piece of a puzzle that's been found.

Why not invest in the future of music, instead of building fortresses to preserve its past?