The overwhelming majority of theories are rejected because they contain bad explanations, not because they fail experimental tests.

The most important application of quantum computing in the future is likely to be a computer simulation of quantum systems, because that's an application where we know for sure that quantum systems in general cannot be efficiently simulated on a classical computer.

The truly privileged theories are not the ones referring to any particular scale of size or complexity, nor the ones situated at any particular level of the predictive hierarchy - but the ones that contain the deepest explanations.

Feeling insignificant because the universe is large has exactly the same logic as feeling inadequate for not being a cow.

Humans may or may not have cosmic significance, and if they do, it will be by hitching a ride on the objective centrality of knowledge in the cosmic scheme of things.

The whole [scientific] process resembles biological evolution. A problem is like an ecological niche, and a theory is like a gene or a species which is being tested for viability in that niche.

Where we have good, testable explanations, they then have to be tested, and we drop the ones that fail the tests.