The really important kind of freedom involves attention, and awareness, and discipline, and effort, and being able truly to care about other people and to sacrifice for them, over and over, in myriad petty little unsexy ways, every day.

It now lately sometimes seemed a black miracle to me that people could actually care deeply about a subject or pursuit, and could go on caring this way for years on end. Could dedicate their entire lives to it. It seemed admirable and at the same time pathetic. We are all dying to give our lives away to something, maybe.

I'll say God seems to have a kind of laid-back management style I'm not crazy about. I'm pretty much anti-death. God looks by all accounts to be pro-death. I'm not seeing how we can get together on this issue, he and I.

...most Substance-addicted people are also addicted to thinking, meaning they have a compulsive and unhealthy relationship with their own thinking.

It took years after I’d graduated from Amherst to realize that people were actually far more complicated and interesting than books, that almost everyone else suffered the same secret fears and inadequacies as I, and that feeling alone and inferior was actually the great valent bond between us all. I wish I’d been smart enough to understand that when I was an adolescent.

[I]f the writer does his job right, what he basically does is remind the reader of how smart the reader is.

She took a sort of abject pride in her mecilessness toward herself.