It is not contrary to reason to prefer the destruction of the whole world to the scratching of my finger. It is not contrary to reason for me to choose my total ruin, to prevent the least uneasiness of an Indian, or person wholly unknown to me. It is as little contrary to reason to prefer even my own acknowledged lesser good to my greater, and have a more ardent affection for the former than the latter.

In public affairs men are often better pleased that the truth, though known to everybody, should be wrapped up under a decent cover than if it were exposed in open daylight to the eyes of all the world.

I never asserted such an absurd thing as that things arise without a cause.

All the sciences have a relation, greater or less, to human nature; and...however wide any of them may seem to run from it, they still return back by one passage or another. Even Mathematics, Natural Philosophy, and Natural Religion, are in some measure dependent on the science of MAN; since they lie under the cognizance of men, and are judged of by their powers and faculties.

A man who has cured himself of all ridiculous prepossessions, and is fully, sincerely, and steadily convinced, from experience as well as philosophy, that the difference of fortune makes less difference in happiness than is vulgarly imagined; such a one does not measure out degrees of esteem according to the rent-rolls of his acquaintance. ... his internal sentiments are more regulated by the personal characters of men, than by the accidental and capricious favors of fortune.

.. that which renders morality an active principle and constitutes virtue our happiness, and vice our misery: it is probable, I say, that this final sentence depends on some internal sense or feeling, which nature has made universal in the whole species.

When I shall be dead, the principles of which I am composed will still perform their part in the universe, and will be equally useful in the grand fabric, as when they composed this individual creature. The difference to the whole will be no greater betwixt my being in a chamber and in the open air. The one change is of more importance to me than the other; but not more so to the universe.