I don't remember any sibling rivalry growing up, because by the time I was really conscious, Tom was going away to college. My relationship with him, which is a very close one, really developed in more recent years.

There's nothing worse than putting two similar shows back-to-back. Viewers don't want to watch one show and then sit through another half-hour of almost the same thing.

There's nothing more powerful than someone who has the disease who can be articulate and go in front of Congress or go to local government and say man, this is what's happening, and it's going to be you.

I think being an actor in general is acknowledging that we are constantly playing different roles, that we have all these different parts of ourselves and instead of pretending that you are just one thing, as an actor you get to admit that you've got all this stuff going on.

So much of life is paradox. So much of life is neither one thing nor the other... it's both things at the same time.

Her lips said 'no', but her eyes said 'read my lips'.

I don't have the time to tell you all the things I've learned from this cast. It's an extraordinary ensemble because we all support each other so well.