The word entrepreneur is associated with success and adventure. From my life, the only thing I can tell you that's consistently associated with entrepreneurship is failure, and the only thing consistently associated with invention is frustration. There is a long road between the idea and the reality.

If you're going to fail, you might as well fail at the big ones.

I consider high-speed data transmission an invention that became a major innovation. It changed the way we all communicate

I think in our lifetime, that level of acceptance of "well, we couldn't do any better," won't be tolerated. We're going to start to see individual therapies customized for individual patients, and it's going to change the way people get healthcare.

As we move towards 8 or 10 billion people on the planet, there's a little less gold per capita. Each one of us will continue to be fighting over an ever smaller percentage of total resources. This is not a happy thought

It’s not what you do – it’s what you are becoming.

Whatever the marketplace, if talented people are given resources, they're going to keep driving us to having better, simpler, cheaper solutions to problems.