The spirit of Texas seems to pervade our everyday existence. Our desire is to be superlative, not only the largest, but also the best in the United States.

I've always felt that maybe one of the reasons that I did well as a student and made such good grades was because I lacked confidence. Lacked self-confidence, and I never felt that I was prepared to take an examination, and I had to study a little bit extra. So that sort of lack of confidence helped me, I think, to make a good record when I was a student.

Get a scalpel, and practice just, say, cutting a piece of meat or something like that. You sort of learn how you want to hold your fingers, and that sort of thing, and try to become graceful when you operate.

I've always felt that I did well as a student because I lacked confidence.

So much goes into doing a transplant operation. All the way from preparing the patient, to procuring the donor. It's like being an astronaut. The astronaut gets all the credit, he gets the trip to the moon, but he had nothing to do with the creation of the rocket, or navigating the ship. He's the privileged one who gets to drive to the moon. I feel that way in some of these more difficult operations, like the heart transplant.

Of the many 'firsts' with which I have been involved at the Texas Heart Institute —including the first successful human heart transplant in the United States and the first total artificial heart transplant in the world—the achievement that may have the greatest impact on health care did not occur in the operating room or in the research laboratory. It happened on a piece of paper... when we created the first-ever packaged pricing plan for cardiovascular surgical procedures.

[The heart is] really a fascinating organ. It's about the only organ in the body that you can really witness its function. Doing things. And so on. Some of the other organs you can witness, like the intestines, will have this sort of peristaltic motion. But nothing that can compare with the activity of the human heart.