We have not yet concluded that needle-exchange programs do not encourage drug use.

Sex education has to do with what's in people's head.

I've spent my whole life with people underestimating me.

I bring other constituencies - I also have ties to minority communities. And obviously, to the world of world-class research universities. So I can bring some constituencies that I'm used to working with.

Every year, I am reminded of the kids who aren't in the freshman class and aren't graduating. I remember every single one of them. That is the worst of times for me, to see the future snuffed out.

I compensate for big risks by always doing my homework and being well-prepared. I can take on larger risks by reducing the overall risk.

I think anyone that thought that we were coming in as a bunch of liberal Democrats to deliver more large-scale social programs was nuts. I sure didn't expect it.