Each of these [bacterial] species are masterpieces of evolution. Each has persisted for thousands to millions of years. Each is exquisitely adapted to the environment in which it lives, interlocked with other species to form ecosystems upon which our own lives depend in ways we have not begun even to imagine.

A paradigm shift is the best a scientist can hope for. Whenever I smell an opportunity like that, I go after it. You have a new discovery that something's working in a different way than you thought. And this is particularly true in molecular and cell biology, which is structural biology and has the least potential for controversy and partisanship among the biological scientists. You're dealing with a concrete object that's either there or not there.

These slender little people (Homo Habilis), the size of modern 12 year olds, were devoid of fangs and claws and almost certainly slower on foot than the four legged animals around them. They could have succeeded in their new way of life only by relying on tools and sophisticated cooperative behavior

Every kid has a bug period... I never grew out of mine.

The world depends on fungi, because they are major players in the cycling of materials and energy around the world.

What's been gratifying is to live long enough to see molecular biology and evolutionary biology growing toward each other and uniting in research efforts.

If history and science have taught us anything, it is that passion and desire are not the same as truth.