A paradigm shift is the best a scientist can hope for. Whenever I smell an opportunity like that, I go after it. You have a new discovery that something's working in a different way than you thought. And this is particularly true in molecular and cell biology, which is structural biology and has the least potential for controversy and partisanship among the biological scientists. You're dealing with a concrete object that's either there or not there.

We've got paleolithic emotions, medieval institutions, and god-like technologies.

The history of life on earth has been a history of interaction between living things and their surroundings.

Science offers the boldest metaphysics of the age. It is a thoroughly human construct, driven by the faith that if we dream, press to discover, explain, and dream again, thereby plunging repeatedly into new terrain, the world will somehow come clearer and we will grasp the true strangeness of the universe. And the strangeness will all prove to be connected, and make sense.

The great paradox of determinism and free will, which has held the attention of the wisest of philosophers and psychologists for generations, can be phrased in more biological terms as follows: If our genes are inherited, and our environment is a train of physical events set in motion before we were born, how can there be a truly independent agent within the brain? The agent itself is created by the interaction of the genes and the environment. It would appear that our freedom is only a self delusion.

Individual versus group selection results in a mix of altruism and selfishness, of virtue and sin, among the members of a society. If one colony member devotes its life to service over marriage, the individual is of benefit to the society, even though it does not have personal offspring. A soldier going into battle will benefit his country, but he runs a higher risk of death than one who does not. An altruist benefits the group, but a layabout or coward who saves his own energy and reduces his bodily risk passes the resulting social cost to others.

No species ... possesses a purpose beyond the imperatives created by genetic history ... The human mind is a device for survival and reproduction, and reason is just one of its various techniques.