As an actor, you can really play the intensity and gravity and seriousness of the moment, and just rely on the circumstances being funny. The joke is kind of the situation you're in, or the way you're reacting to something, as opposed to the characters just saying something witty.

It's kind of hard to win most elections on anti-family, immorality, and Satan-worship.

I didn't mention the tooth thing to anyone until it became clear that...we started to discuss just taking it out of the movie [The Hangover] because we couldn't find anything that worked and they couldn't afford to do a full like digital effect. So that's when I called my dentist and it worked out.

Who among us wouldn't rush out and buy a Pepsi if we thought it would make the Osborne's disappear?

It has been said that a rolling stone gathers no moss. I would add that sometimes a rolling stone also gathers no verifiable facts or even the tiniest morsels of journalistic integrity.

I'm pretty sure no one's reading action scripts saying, 'This has got to be Ed Helms.'

I'm sort of laughing and so Zach [ Galifianakis] started laughing [on the set of The Hangover]. And Todd [Phillips] was baffled because what we were saying wasn't that funny, you know what I mean? And it was like all the baby's face. So Todd was like, 'What is going on? Get it together guys.'