When we were not shooting [The Hangover] we were sleeping, so pretty much every waking moment we spent together. And, you know, Bradley [Cooper], Zach [Galifianakis] and I were acquaintances before the movie started but we became good friends very quickly and spent so much time together that it was just inevitable we were either going to really hate each other or really like each other. Thank god it turned out to be the latter.

I loved the show Lost, in part because the writers were so nimble in how they would take things from previous episodes, that probably weren't created with any intent towards a larger narrative, and they would get woven into narratives in a really elegant and exciting way.

It has been said that a rolling stone gathers no moss. I would add that sometimes a rolling stone also gathers no verifiable facts or even the tiniest morsels of journalistic integrity.

That's actually a rare thing to be on a set full of people that you admire and make you laugh all the time.

When I was 15 I lost a tooth and had an implant put in. Cut to 20 years later, I'm doing this part [Andy Bernard] and the script calls for my character to lose a tooth.

As an actor, you can really play the intensity and gravity and seriousness of the moment, and just rely on the circumstances being funny. The joke is kind of the situation you're in, or the way you're reacting to something, as opposed to the characters just saying something witty.

Let's just say it was damn hard [to make the Hangover]. I've got the bumps and bruises to show for it. It's funny because things that don't even look that bad on screen were still extremely painful.