Don't be afraid of fear. Because it sharpens you, it challenges you, it makes you stronger; and when you run away from fear, you also run away from the opportunity to be your best possible self.

I'm pretty sure no one's reading action scripts saying, 'This has got to be Ed Helms.'

Shouldn't EVERY week be Infection Control Week?

Let's just say it was damn hard [to make the Hangover]. I've got the bumps and bruises to show for it. It's funny because things that don't even look that bad on screen were still extremely painful.

I had envisioned doing comedy since childhood. For sure.

The improv stuff, that's always surprising so a lot of times that's really funny.

When you're in New York City or Los Angeles, even if you're not dealing with show business, there's still this sense that it's the center of the universe. And I think that's a really dangerous, limiting mindset.