Earlier this week ... scientists announced the completion of a task that once seemed unimaginable; and that is, the deciphering of the entire DNA sequence of the human genetic code. This amazing accomplishment is likely to affect the 21st century as profoundly as the invention of the computer or the splitting of the atom affected the 20th century. I believe that the 21st century will be the century of life sciences, and nothing makes that point more clearly than this momentous discovery. It will revolutionize medicine as we know it today.

With Barack Obama, we will turn the page on the old politics of misrepresentation and distortion. With Barack Obama we will close the book on the old politics of race against race.

Never listen to a phone call that isn't meant for you. Never read a letter that isn't meant for you. Never pay attention to a comment that isn't meant for you. Never violate people's privacy. You will save yourself a lot of anguish.

I believe that the Constitution is not hostile to the idea that national problems can be solved at the national level through the cooperative efforts of the three coequal branches of government, the Congress, the executive and courts. But not every president, not every legislator and not every judge agrees that the federal government has the power to address and to try to remedy the twin national problems of poverty and access to equal opportunity.

Legal immigrants play by the rules and come in under the law. They work, raise their families, pay taxes, and serve in the Armed Forces. ... Legal immigrants do not seek to cross the border, or overstay their visas. They come here the right way. ... And, by and large, they are here as the result of reunifying families.

In an era when America is still too divided by race and by riches, Judge [Samuel] Alito has not written one single opinion on the merits in favor of a person of color alleging race discrimination on the job: in 15 years on the bench, not one.

I don't think America can just drill itself out of its current energy situation. We don't need to destroy the environment to meet our energy needs. We need smart, comprehensive, common-sense approaches that balance the need to increase domestic energy supplies with the need to maximize energy efficiency.