The best weapon of a dictatorship is secrecy; the best weapon of a democracy is openness.

Knowing he [Bob Serber] was going to the [first atom bomb] test, I asked him how he planned to deal with the danger of rattlesnakes. He said, 'I'll take along a bottle of whiskey.' … I ended by asking, 'What would you do about those possibilities [of what unknown phenomena might cause a nuclear explosion to propagate in the atmosphere]?' Bob replied, 'Take a second bottle of whiskey.'

The scientist is not responsible for the laws of nature. It is his job to find out how these laws operate. It is the scientist's job to find the ways in which these laws can serve the human will. However, it is not the scientist's job to determine whether a hydrogen bomb should be constructed, whether it should be used, or how it should be used. This responsibility rests with the American people and with their chosen representatives.

Today's science is tomorrow's technology.

A state-of-the-art calculation requires 100 hours of CPU time on the state-of-the-art computer, independent of the decade.

A fact is a simple statement that everyone believes. It is innocent, unless found guilty. A hypothesis is a novel suggestion that no one wants to believe. It is guilty, until found effective.

When you come to the end of all the light you know, and it's time to step into the darkness of the unknown, faith is knowing that one of two things shall happen: either you will be given something solid to stand on or you will be taught to fly.