Knowing he [Bob Serber] was going to the [first atom bomb] test, I asked him how he planned to deal with the danger of rattlesnakes. He said, 'I'll take along a bottle of whiskey.' … I ended by asking, 'What would you do about those possibilities [of what unknown phenomena might cause a nuclear explosion to propagate in the atmosphere]?' Bob replied, 'Take a second bottle of whiskey.'

When Columbus took off, the purpose was to improve trade relations with China. That problem has not been solved to this very day, but just look at the by-products.

It is often claimed that knowledge multiplies so rapidly that nobody can follow it. I believe this is incorrect. At least in science it is not true. The main purpose of science is simplicity and as we understand more things, everything is becoming simpler. This, of course, goes contrary to what everyone accepts.

The scientist is not responsible for the laws of nature. It is his job to find out how these laws operate. It is the scientist's job to find the ways in which these laws can serve the human will. However, it is not the scientist's job to determine whether a hydrogen bomb should be constructed, whether it should be used, or how it should be used. This responsibility rests with the American people and with their chosen representatives.

My experience has been in a short 77 years that in the end when you fight for a desperate cause and have good reasons to fight, you usually win.

Today's science is tomorrow's technology.

I am guilty of the great crime of optimism.