As for the forces, electromagnetism and gravity we experience in everyday life. But the weak and strong forces are beyond our ordinary experience. So in physics, lots of the basic building blocks take 20th- or perhaps 21st-century equipment to explore.
Edward WittenQuantum mechanics brought an unexpected fuzziness into physics because of quantum uncertainty, the Heisenberg uncertainty principle. String theory does so again because a point particle is replaced by a string, which is more spread out.
Edward Witten