That's the thing I want to make clear about depression: It's got nothing at all to do with life. In the course of life, there is sadness and pain and sorrow, all of which, in their right time and season, are normal-unpleasant, but normal. Depression is an altogether different zone because it involves a complete absence: absence of affect, absence of feeling, absence of response, absence of interest. The pain you feel in the course of a major clinical depression is an attempt on nature's part (nature, after all, abhors a vacuum) to fill up the empty space.

As someone very sagely said during the parricide trials of the Menendez Brothers: anytime your kids kill you, you are at least partly to blame.

Everything's plastic, we're all going to die sooner or later, so what does it matter.

The brief relief of seeing other people when I leave my room turns into a desperate need to be alone, and then being alone turns into a terrible fear that I will have no friends, I will be alone in this world and in my life. I will eventually be so crazy from this black wave, which seems to be taking over my head with increasing frequency, that one day I will just kill myself, not for any great, thoughtful existential reasons, but because I need immediate relief.

In a typical mental health catch-22, the alienating nature of depression tends to keep its sufferers from finding their way to the very support groups that might help them.

I start to get the feeling that something is really wrong.

I always carry lots of stuff with me wherever I roam, always weighted down with books, with cassettes, with pens and paper, just in case I get the urge to sit down somewhere, and oh, I don't know, read something or write my masterpiece.