Desire leaves us heartbroken; it wears us out.

I was raised by drag queens, practically ... my mother died when I was four-years-old, so I was effectively raised by a bunch of different people. A lot of those people were friends of my sister, Kathleen, who had all these gay friends. She would baby-sit me everyday, and she would take me over to her friend's houses with all kinds of things going on: tucking, and eyebrow drawing, waxing, all sorts of things. I was literally raised by gay men.

Thank god Shonda Rhimes had this agenda to make television look like life, to make it look like the real world.

If I'm bringing joy to people and entertaining people as an actor, then I should be grateful for that and act accordingly, you know?

The older you get the more realistic it is that you're significant other is your significant other. I mean, you'll always have your girlfriends or your guy friends, but the person you're married to is usually your No. 1.

Can you get any better than Patrick Dempsey? I don't think so!

Cancer is something that touches everyone's lives.