Focus on something that has high value to someone else, be really rigorous in making that assessment, because natural human tendency is wishful thinking, so the challenge to entrepreneurs is telling what's the difference between really believing in your ideals and sticking to them as opposed to pursuing some unrealistic dream that doesn't actually have merit, be very rigorous in your self analysis, certainly being extremely tenacious, and just work like hell. Put in 80-100 hours every week. All these things improves the odds of success

I just want to retire before I go senile because if I don't retire before I go senile, then I'll do more damage than good at that point.

I think the high-tech industry is used to developing new things very quickly. It's the Silicon Valley way of doing business: You either move very quickly and you work hard to improve your product technology, or you get destroyed by some other company.

You need to live in a dome initially but over time you could terraform Mars to look like Earth and eventually walk around outside without anything on. ... So it's a fixer-upper of a planet.

One bit of advice: it is important to view knowledge as sort of a semantic tree - make sure you understand the fundamental principles, ie the trunk and big branches, before you get into the leaves/details or there is nothing for them to hang on to.

If you think back to the beginning of cell phones, laptops or really any new technology, it's always expensive.

I think you should always be seeking negative feedback.