The narrow slit through which the scientist, if he wants to be successful, must view nature constructs, if this goes on for a long time, his entire character; and, more often than not, he ends up becoming what the German language so appropriately calls a Fachidiot (professional idiot).

One of the most insidious and nefarious properties of scientific models is their tendency to take over, and sometimes supplant, reality.

We manipulate nature as if we were stuffing an Alsatian goose. We create new forms of energy; we make new elements; we kill crops; we wash brains. I can hear them in the dark sharpening their lasers.

There are no such men today. We have created a mechanism that makes it practically impossible for a real genius to appear. In my own field the biochemist Fritz Lipmann or the much maligned Linus Pauling were very talented people. But generally, geniuses everywhere seem to have died out by 1914. Today, most are mediocrities blown up by the winds of the time.

Scientific fashions last longer than women's fashions but not as long as men's

If you can modify a cell, it's only a short step to modifying a mouse, and if you can modify a mouse, it's only a step to modifying a higher animal, even man.

The modern version of Buridan's ass [a figurative description of a man of indecision] has a Ph.D., but no time to grow up as he is undecided between making a Leonardo da Vinci in the test tube or planting a Coca Cola sign on Mars.