The results serve to disprove the tetranucleotide hypothesis. It is, however, noteworthy-whether this is more than accidental, cannot yet be said-that in all desoxypentose nucleic acids examined thus far the molar ratios of total purines to total pyrimidines, and also of adenine to thymine and of guanine to cytosine, were not far from 1.
Erwin ChargaffOne of the most insidious and nefarious properties of scientific models is their tendency to take over, and sometimes supplant, reality.
Erwin Chargaff