When a drug comes out [that's broadly prescribed] there are going to start to be a lot of people on it [in a million person cohort] and you might get therefore an early signal of something unexpected that hadn't come through in the clinical trials. And I'm sure [drug companies] would love it if, in fact, FDA, recognizing that, would say, OK, maybe you don't have to do your trial with 30,000 people because we're going to find out shortly after registration because we'll have a lot of people taking the drug and we'll be able to see what happened using PMI.
Francis Collins[Decoding the human genome sequence] is the most significant undertaking that we have mounted so far in an organized way in all of science. I believe that reading our blueprints, cataloguing our own instruction book, will be judged by history as more significant than even splitting the atom or going to the moon.
Francis CollinsMy daughter is a practicing physician so believe me I get a lot of the frustration from her. You get it from patients. For me personally, when I ask my doctor to send me my record, what I get is a scanned PDF of his hard copy! This is not good. It would be hopeless to work with a million people if you had to do this on paper, and one of the reasons this is the right time for this is because of the existence of EHRs.
Francis Collins