Since I essentially knew nothing, I had an almost completely free choice.
Chance is the only source of true novelty.
Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
Exact knowledge is the enemy of vitalism.
Again the message to experimentalists is: Be sensible but don't be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
In my experience most mathematicians are intellectually lazy.