A commonsense interpretation of the facts suggests that a superintellect has monkeyed with physics, as well as with chemistry and biology, and that there are no blind forces worth speaking about in nature. The numbers one calculates from the facts seem to me so overwhelming as to put this conclusion almost beyond question.
Fred HoyleImagine 1050 blind persons each with a scrambled Rubik's cube, and try to conceive of the chance of them all simultaneously arriving at the solved form. You then have a chance of arriving by random shuffling, of just one of the many biopolymers on which life depends. The notion that not only the biopolymers but the operating program of a living cell could be arrived at by chance in a primordial organic soup here on the Earth is evidently nonsense of a high order.
Fred HoyleIt is ironic that the scientific facts throw Darwin out, but leave William Paley, a figure of fun to the scientific world for more than a century, still in the tournament with a chance of being the ultimate winner... Indeed, such a theory is so obvious that one wonders why it is not widely accepted as being self-evident. The reasons are psychological rather than scientific.
Fred HoyleLife cannot have had a random beginning. ... The trouble is that there are about two thousand enzymes, and the chance of obtaining them all in a random trial is only one part in 10 to the 40,000 power, an outrageously small probability that could not be faced even if the whole universe consisted of organic soup.
Fred Hoyle