In the future, a new generation of artists will be writing genomes as fluently as Blake and Byron wrote verses.

Now, as Mandelbrot points out, ... Nature has played a joke on the mathematicians. The 19th-century mathematicians may not have been lacking in imagination, but Nature was not. The same pathological structures that the mathematicians invented to break loose from 19th-century naturalism turn out to be inherent in familiar objects all around us.

It is in the long run essential to the growth of any new and high civilization that small groups of men can escape from their neighbors and from their government, to go and live as they please in the wilderness. A truly isolated, small, and creative society will never again be possible on this planet.

There are three reasons, . . . apart from scientific considerations, mankind needs to travel in space. The first . . . is garbage disposal; we need to transfer industrial processes into space so that the earth may remain a green and pleasant place for our grandchildren to live in. The second . . . to escape material impoverishment: the resources of this planet are finite, and we shall not forego forever the abundance of solar energy and minerals and living space that are spread out all around us. The third . . . our spiritual need for an open frontier.

When the great innovation appears, it will almost certainly be in muddled, incomplete and confusing form. ... For any speculation which does not at first glance look crazy, there is no hope.

Scepticism is as important for a good journalist as it is for a good scientist.

The biggest breakthrough in the next 50 years will be the discovery of extraterrestrial life. We have been searching for it for 50 years and found nothing. That proves life is rarer than we hoped, but does not prove that the universe is lifeless. We are only now developing the tools to make our searches efficient and far-reaching, as optical and radio detection and data processing move forward.