The technologies which have had the most profound effects on human life are usually simple. A good example of a simple technology with profound historical consequences is hay. Nobody knows who invented hay, the idea of cutting grass in the autumn and storing it in large enough quantities to keep horses and cows alive through the winter. All we know is that the technology of hay was unknown to the Roman Empire but was known to every village of medieval Europe. Like many other crucially important technologies, hay emerged anonymously during the so-called Dark Ages.

I think that the artificial-intelligence people are making a lot of noise recently, claiming that artificial intelligence is making huge progress and we're going to be outstripped by the machines.

The biggest breakthrough in the next 50 years will be the discovery of extraterrestrial life. We have been searching for it for 50 years and found nothing. That proves life is rarer than we hoped, but does not prove that the universe is lifeless. We are only now developing the tools to make our searches efficient and far-reaching, as optical and radio detection and data processing move forward.

For me, science is just a bunch of tools - it's like playing the violin.

That's the beautiful thing about science - that it's all about things we don't understand, not just the things we do understand.

The whole point of science is that most of it is uncertain. That's why science is exciting--because we don't know. Science is all about things we don't understand. The public, of course, imagines science is just a set of facts. But it's not. Science is a process of exploring, which is always partial. We explore, and we find out things that we understand. We find out things we thought we understood were wrong. That's how it makes progress.

In the future, a new generation of artists will be writing genomes as fluently as Blake and Byron wrote verses.