I, Galileo, son of the late Vicenzo Galilei, swear that I never said that the prime numbers are useless. What I said was that you cannot count lunar craters by counting 2, 3, 5, 7.

Oh, my dear Kepler, how I wish that we could have one hearty laugh together. Here, at Padua, is the principal professor of philosophy, whom I have repeatedly and urgently requested to look at the moon and planets through my glass, [telescope] which he pertinaciously refuses to do. Why are you not here? what shouts of laughter we should have at this glorious folly! and to hear the professor of philosophy at Pisa laboring before the grand duke with logical arguments, as if with magical incantations, to charm the new planets out of the sky.

Vision, I say, is related to light itself. But of this sensation and the things pertaining to it, I pretend to understand but little; and since even a long time would not suffice to explain that trifle, or even to hint at an explanation, I pass over this in silence.

Nothing occurs contrary to nature except the impossible, and that never occurs.

Nature...does not act by means of many things when it can do so by means of a few.

Science proceeds more by what it has learned to ignore than what it takes into account.

In time you may discover everything that can be discovered, and still your progress will only be progress away from humanity. The distance between you and them can one day become so great that your joyous cry over some new gain could be answered by an universal shriek of horror.