That sculpture is more admirable than painting for the reason that it contains relief and painting does not is completely false. ... Rather, how much more admirable the painting must be considered, if having no relief at all, it appears to have as much as sculpture!

Two truths cannot contradict one another.

I think that in the discussion of natural problems we ought to begin not with the Scriptures, but with experiments, and demonstrations.

But what exceeds all wonders, I have discovered four new planets and observed their proper and particular motions, different among themselves and from the motions of all the other stars; and these new planets move about another very large star [Jupiter] like Venus and Mercury, and perchance the other known planets, move about the Sun. As soon as this tract, which I shall send to all the philosophers and mathematicians as an announcement, is finished, I shall send a copy to the Most Serene Grand Duke, together with an excellent spyglass, so that he can verify all these truths.

Nature is relentless and unchangeable, and it is indifferent as to whether its hidden reasons and actions are understandable to man or not.

I would beg the wise and learned fathers (of the church) to consider with all diligence the difference which exists between matters of mere opinion and matters of demonstration. ... [I]t is not in the power of professors of the demonstrative sciences to alter their opinions at will, so as to be now of one way of thinking and now of another. ... [D]emonstrated conclusions about things in nature of the heavens, do not admit of being altered with the same ease as opinions to what is permissible or not, under a contract, mortgage, or bill of exchange.

Holy Scripture could never lie or err...its decrees are of absolute and inviolable truth.